What are microcarriers made of?
Microcarriers can be made from a number of different materials including DEAE-dextran, glass, polystyrene plastic, acrylamide, collagen, and alginate. These microcarrier materials, along with different surface chemistries, can influence cellular behavior, including morphology and proliferation.
What is microcarrier cell culture?
In microcarrier culture, cells grow as monolayers on the surface of small spheres or as multilayers in the pores of macroporous structures that are usually suspended in culture medium by gentle stirring.
What is Synthemax?
Overview. Corning Synthemax vitronectin self-coating substrate is a unique, animal-free, synthetic vitronectin-based peptide containing the RGD motif and flanking sequences.
What are microcarrier beads?
Microcarriers are small polymeric beads with a diameter of approximately 100–300 μm and a surface designed to promote cell attachment. Both microporous and macroporous microcarriers can be used in stirred-tank bioreactors, and macroporous carriers can also be used in packed-bed bioreactors as previously described.
What are the microcarriers of Corning synthemax II?
These microcarriers are Synthemax® II surface treated to enhance cell attachment, maximizing cell yield and viability. The unique Corning Synthemax II substrate creates a synthetic surface on the microcarriers for stem cell expansion
How are synthemax 2 microcarriers used in bioreactors?
The microcarriers are sterile, ready to use, and available in closed systems packaging to be used directly with bioreactors. These microcarriers are Synthemax II surface treated to enhance cell attachment, maximizing cell yield and viability.
How are Corning microcarriers used for stem cell expansion?
Corning Synthemax® II substrate creates a synthetic surface on the microcarriers for stem cell expansion. For use with MSC and iPS/ES applications. (Animal Origin Free) Corning CellBIND® surface treatment infuses the surface of the microcarriers with oxygen to improve cell attachment.
How are Corning microcarriers used in bioreactors?
Corning Microcarriers are designed to simplify your scale-up processes. The microcarriers are sterile, ready to use, and available in closed systems packaging to be used directly with bioreactors. These microcarriers are Synthemax II surface treated to enhance cell attachment, maximizing cell yield and viability.
