What is the difference between DNA polymerase 1/2 and 3?

What is the difference between DNA polymerase 1/2 and 3?

The key difference between DNA polymerase 1 2 and 3 mainly relies on the prime function of each enzyme. DNA polymerase 3 is the main enzyme which catalyzes the DNA synthesis, while DNA polymerase 1 and 2 are involved in DNA repairing and proofreading.

What are the function of DNA polymerase 1/2 and 3?

Different DNA polymerases perform specific functions. In prokaryotes, DNA polymerase III is the main enzyme responsible for replication. DNA polymerase I and II have a role to play in repair, removing the primer and filling the gaps. In eukaryotes, DNA polymerase 𝝳 is the main enzyme for replication.

How is DNA polymerase 1 and 3?

The main difference between DNA polymerase 1 and 3 is that DNA polymerase 1 is involved in the removal of primers from the fragments and replacing the gap by relevant nucleotides whereas DNA polymerase 3 is mainly involved in the synthesis of the leading and lagging strands.

What is the function of DNA polymerase 3 & 1?

DNA polymerase 3 is essential for the replication of the leading and the lagging strands whereas DNA polymerase 1 is essential for removing of the RNA primers from the fragments and replacing it with the required nucleotides. These enzymes cannot replace each other as both have different functions to be performed.

What is the function of polymerase 2?

RNA polymerase II catalyzes the synthesis of precursor mRNA. In eukaryotes, this RNA is generally longer than the final or “mature” mRNA, whose molecule is used as a template for protein synthesis.

What is the function of DNA polymerase 3 in DNA replication?

Synthesis of DNA DNA polymerase III will then synthesize a continuous or discontinuous strand of DNA, depending if this is occurring on the leading or lagging strand (Okazaki fragment) of the DNA. DNA polymerase III has a high processivity and therefore, synthesizes DNA very quickly.

What is the function of DNA polymerase?

The main function of DNA polymerase is to synthesize DNA from deoxyribonucleotides, the building blocks of DNA. The DNA copies are created by the pairing of nucleotides to bases present on each strand of the original DNA molecule.

What does DNA polymerase 3 do?

DNA polymerase 3 is the main enzyme involved in prokaryotic DNA replication. DNA polymerase 3 possesses 5’ to 3’ polymerization activity where new nucleotides are added to the growing chain at its 3’ end. The enzyme aids the base pairing of incoming nucleotides with the template strand.

What is polymerase II?

DNA polymerase II (also known as DNA Pol II or Pol II ) is a prokaryotic DNA-Dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an 89.9-kDa protein and is a member of the B family of DNA polymerases .

About the Author

You may also like these