What is nitazoxanide tablet used for?
Nitazoxanide is used to treat diarrhea in children and adults caused by the protozoa Cryptosporidium or Giardia. Protozoa are suspected as the cause when diarrhea lasts more than 7 days. Nitazoxanide is in a class of medications called antiprotozoal agents.
What is the mechanism of action of nitazoxanide?
Mechanism Of Action The antiprotozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic energy metabolism.
Can alinia cause diarrhea?
Common side effects of nitazoxanide include: Diarrhea. Nausea. Abdominal pain.
Is nitazoxanide an antiparasitic?
Nitazoxanide is a new thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of protozoa and helminths. It is given by the oral route with good bioavailability and is well tolerated, with primarily mild gastrointestinal side effects.
How long should you use nitazoxanide?
Adults and children 12 years or older—25 milliliters (mL) every 12 hours, taken with food, for 3 days. Children 4 to 11 years of age—10 mL every 12 hours, taken with food, for 3 days.
Is nitazoxanide an antibiotic?
Nitazoxanide (NTZ) is an antibiotic with microbiological characteristics similar to those of metronidazole but without an apparent problem of resistance. The aim of this study was the prospective evaluation of NTZ given as a single agent in the treatment of Helicobacter pylori infection.
Can nitazoxanide treat amoeba?
Nitazoxanide is effective in treating invasive intestinal amoebiasis and in eliminating E. histolytica colonisation of the intestinal tract. Further studies are warranted in patients with hepatic amoebiasis.
How long does nitazoxanide stay in your system?
Nitazoxanide
| Clinical data | |
|---|---|
| Metabolism | Rapidly hydrolyzed to tizoxanide |
| Metabolites | tizoxanide tizoxanide glucuronide |
| Elimination half-life | 3.5 hours |
| Excretion | Kidney, bile duct, and fecal |
How long does nitazoxanide take to work?
How rapidly does the drug work? It may take up to 5 days for diarrhea to resolve in approximately 80% of patients 4.
Does nitazoxanide change urine Colour?
Common side effects may include: nausea, stomach pain; headache; or. discolored urine.
Is nitazoxanide used to treat H pylori?
Conclusions: Nitazoxanide-based treatments appear to be an effective treatment for H. pylori. While the ideal NTZ combination therapy is uncertain, a combination with a proton-pump inhibitor and one to two antibiotics has demonstrated the highest rates of H. pylori eradication.
What are the side effects of nitazoxanide 500 mg?
Alinia (Nitazoxanide) 500 mg tablets are FDA-approved for the treatment of Cryptosporidium Parvum & Giardia Lamblia infections in adults and kids 12 and over
What kind of diarrhea is nitazoxanide used for?
What is nitazoxanide? Nitazoxanide is an antiprotozoal medicine that treats infections caused by protozoa (single-cell parasites that live in moist places such as lakes, streams, and soil). Nitazoxanide is used to treat diarrhea caused by Giardia or Cryptosporidium. These conditions are sometimes called ” Traveler’s diarrhea .”
What are the different brand names of nitazoxanide?
Brand names. Nitazoxanide is sold under the brand names Adonid, Alinia, Allpar, Annita, Celectan, Colufase, Daxon, Dexidex, Diatazox, Kidonax, Mitafar, Nanazoxid, Parazoxanide, Netazox, Niazid, Nitamax, Nitax, Nitaxide, Nitaz, Nizonide, NT-TOX, Pacovanton, Paramix, Toza, and Zox.
How old do you have to be to take nitazoxanide tablets?
Tell all of your health care providers that you take this medicine (nitazoxanide tablets). This includes your doctors, nurses, pharmacists, and dentists. Do not give to a child younger than 12 years of age. Tell your doctor if you are pregnant or plan on getting pregnant.
