What is the treatment for neuroleptic malignant syndrome?
Medications prescribed as treatment may include skeletal muscle relaxants, such as dantrolene; stimulators of dopamine production and activity, such as bromocriptine; and/or continuous perfusion of central nervous system depressants, such as diazepam.
How do you manage a patient who develops neuroleptic malignant syndrome?
Treatment of patients with neuroleptic malignant syndrome may include the following:
- Benzodiazepines for restraint may be useful.
- Stop all neuroleptics.
- Correct volume depletion and hypotension with intravenous fluids.
- Reduce hyperthermia.
What is the course of NMS?
Neuroleptic malignant syndrome (NMS) is a rare, but life-threatening, idiosyncratic reaction to neuroleptic medications that is characterized by fever, muscular rigidity, altered mental status, and autonomic dysfunction. NMS often occurs shortly after the initiation of neuroleptic treatment, or after dose increases.
How can you prevent neuroleptic malignant syndrome?
The most important aspect of treatment is prevention. This includes reducing risk factors (e.g. dehydration, agitation and exhaustion), early recognition of suspected cases and prompt discontinuation of the offending agent.
How does neuroleptic malignant syndrome happen?
Neuroleptic malignant syndrome (NMS) is a severe disorder caused by an adverse reaction to medications with dopamine receptor-antagonist properties or the rapid withdrawal of dopaminergic medications.
Is a neuroleptic the same the as an antipsychotic?
They are the same thing. They are often considered the same thing, but the differences are subtle. Neuroleptics are in the class on antipsychotics, and these days almost all antipsychotics are neuroleptics. This has not always been true. Almost all antipsychotics depress some form of nerve function in the brain.
What is the prognosis of neuroleptic malignant syndrome (NMS)?
Neuroleptic malignant syndrome prognosis What is neuroleptic malignant syndrome Neuroleptic malignant syndrome (NMS) is a life-threatening, neurological disorder most often caused by an adverse reaction associated with the use of dopamine-receptor antagonist medications or with rapid withdrawal of dopaminergic medications 1) .
How do you treat NMS?
NMS is a medical emergency. Treatment consists of immediate cessation of the offending medication and provision of supportive measures (hydration and cooling).
What does the medical term neuroleptic malignant syndrome mean?
What Is Neuroleptic Malignant Syndrome? Neuroleptic malignant syndrome (NMS) is a rare reaction to antipsychotic drugs that treat schizophrenia, bipolar disorder, and other mental health conditions. It affects the nervous system and causes symptoms like a high fever and muscle stiffness.
