What medication is used for obstetric cholestasis?
Taking a prescription drug called ursodiol (Actigall, Urso, Urso Forte), which helps to lower the level of bile in your blood. Other medications to relieve itching may also be an option. Soaking itchy areas in cool or lukewarm water.
How quickly does Ursodiol work for cholestasis?
Patients receiving the highest dose of ursodiol often have been shown to have the lowest percentage of lithocholic acid in the bile. During treatment with ursodiol for dissolution of gallstones, symptoms of biliary distress began to improve after three to six weeks.
How effective is Ursodiol for cholestasis?
Results. When compared to women with all other treatments (n = 29), ursodiol treated women (n = 15) were found not to differ in clinical characteristics or biochemical parameters. Ursodiol was associated with at least partial relief of pruritus in 14 women (93%).
Can ICP go away on its own?
The causes of ICP/OC usually self-correct without any extra treatment when you have had your baby. You should have a blood test 6-12 weeks after the baby has been born to be sure. If by six months your levels have not returned to normal then you should have more tests for other possible liver conditions.
Which is the best medicine for cholestasis of pregnancy ( ICP )?
Ursodeoxycholic Acid (UDCA), also known as Actigall or Ursodiol or Urso is currently the front-line medication for the treatment of ICP. UDCA is a naturally occurring bile acid that improves liver function and helps reduce total bile acid concentration in the bloodstream.
Why does ICP need to be treated during pregnancy?
This is the reason why it needs to be treated appropriately and adequately. The most important part of management of ICP includes regular monitoring of the pregnant woman for increasing bile acids in blood that could harm the baby.
Where is the highest incidence of ICP in the world?
The incidence of ICP also shows a striking geographical pattern, with a higher prevalence in Scandinavia and South America specifically Chile where the reported prevalence is as high as 15.6%. Mothers and sisters of patients are also at higher risk of developing the condition, proving that there is a definite genetic predisposition.
How to find out if your medicine is safe during pregnancy?
See if there is a registry for your medicine. The FDA Office of Women’s Health offers resources to help women and healthcare providers get informed about medicines and other products used during pregnancy. Use the Pregnancy Social Media Toolkit to inform pregnant women in your network about medication safety.
