Is octanol a lipid?
See also A Databank of Evaluated Octanol-Water Partition Coefficients (LOGKOW), URL: http://logkow.cisti.nrc.ca/logkow/index.jsp. Cells are mainly made of lipids and they are generally modeled as a lipid bilayer model, with a long hydrophobic (water disliking) chain and a polar hydrophilic (water liking) end.
What is the pKa of octanol?
16.84
Structure for FDB012583 (1-Octanol)
| Property | Value | Source |
|---|---|---|
| pKa (Strongest Acidic) | 16.84 | ChemAxon |
| pKa (Strongest Basic) | -2 | ChemAxon |
| Physiological Charge | 0 | ChemAxon |
| Hydrogen Acceptor Count | 1 | ChemAxon |
What is the density of 1-octanol?
824 kg/m³
Octanol/Density
What does 1-octanol smell like?
Aromatic
1-Octanol
| Names | |
|---|---|
| Molar mass | 130.231 g·mol−1 |
| Appearance | Colorless liquid |
| Odor | Aromatic |
| Density | 0.83 g/cm3 (20 °C) |
What does pKa tell you about solubility?
The higher the pKa, the stronger the acid ( the more dissociated into protons). This diagram depicts the effect of a change in pH on the lipid solubility of a weak acid. Seeing as many drugs are either weak acids or weak bases, they will either be charged or uncharged in solutions with different pH.
What is the solubility of 1-octanol in water?
The solubility of water in 1-octanol was measured from 2 °C to 96 °C by coulometric Karl Fischer titration. The mass fraction solubility at 25 ° was found to be (48.91 ± 0.13) mg/g.
Does 1-octanol dissolve in water?
1-octanol is not soluble in water beacuse the large, eight carbon alkyl group dominates the intermolecular forces found in the molecule. Since the large R-group forms significantly large dispersion forces which water cannot break up, the compound is water insoluble.
